Welcome to Mayo Clinic in Rochester, Minnesota, the original and largest Mayo Clinic campus. Located in the heart of Rochester, Minnesota - a dynamic city just 90 minutes south of the Twin Cities of Minneapolis and St. Paul - Mayo Clinic has been safely caring for patients from around the world for more than 100 years.
Mayo Clinic will always be your safe care destination.
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- Michael Ackerman, MD - Director Pediatric and Genetics
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- Joseph Dearani, MD - Surgery
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- Mackram Eleid, MD
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- Bernard Gersh, MD
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- Jeffrey Geske, MD - Director Research
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- Kyle Klarich, MD
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- Darrel (Brian) Newman, MD
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- Steve Ommen, MD - Program Director
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- Hartzell Schaff, MD – Surgery
The city of Rochester, MN revolves around the Mayo Clinic, and is often called “Med City,” resulting in an abundance of options for lodging, food, and activities for patients and their travel companions. Minnesota is the land of 10,000 lakes, and Rochester is tucked into the southeast corner of the state, close to both Wisconsin and Iowa. While the spring, summer, and fall at the Mayo Clinic provide for some milder temperatures, visitors at all times of year, but particularly during the harsh Minnesota winter, should come prepared to bundle up. Don’t forget to check the weather a few days before you visit. There is a system of tunnels on the Downtown Campus of the Mayo Clinic, called the Skyway/Subway, that connects several of the Clinic’s main buildings to a food court, shops, and a number of hotels. If you stay in one of those hotels, you can get to your COE appointment without venturing outside.
Click here to learn the basics for Mayo Clinic patients and visitors. For a deep dive into all of your travel options, expand each of the categories provided on this page. To dig into local lodging, including hotels and short-term rentals, scroll down, and click on the tab of your choice.
Lodging
There is no shortage of available hotels and short-term rentals in the Rochester, MN area, so your choice of where to stay depends largely on your preferences. Start here for an overview. Click on the tabs above for our specific recommendations.
A few items of note:
- The Center of Excellence itself is located in the Mayo building at 200 1st Avenue SW on the Main Campus in Downtown Rochester. Many surgeries and procedures are done at the hospital on the Saint Mary’s Campus. You may want to select lodging that is closer to one or the other. There is a free shuttle that travels back and forth between the two.
- Anderson Wheelchair Rentals (507-512-7899) is a great source for medical equipment and supply rentals, such as reclining chairs, adjustable beds, and bathroom safety items, and they deliver locally.
Hotels
The annual average nightly hotel room rate in Rochester, MN (excluding taxes) is $133 in 2024.
To begin your hotel search, click here, and set the filters on the left to search for all of the typical amenities you seek. Outside of the usual filters such as free parking, free continental breakfast, and high-speed wireless internet, there are Mayo Clinic-specific filters available.
We’ve pre-filtered a few of them for you here:
- Hotels connected to the Skyway/Subway
- Hotels with proximity to the Saint Mary’s Campus
- Hotels with a Courtesy Shuttle to the Mayo Clinic
- Hotels with a Free Shuttle to the Rochester Airport
We’ve also researched some HCM patient-friendly amenities you may wish to take advantage of, including patient pricing discounts, connecting rooms, kitchenette, and the availability of recliners. Many lodging options that do not include a kitchenette do have refrigerators and/or microwaves available to guests. You may need to request them in advance.
We hope you’ll use the list below to assist in your hotel search:
Best Western Rochester (507-289-8866)
3-star hotel; 10% discount for Mayo Clinic patients; call in advance to request the medical reclining chair; connecting rooms are available but not guaranteed.
- COE Discount Available
- Recliner Available
- Connecting Rooms Available
- Handicap Accessible
- Courtesy Clinic Shuttle
EVEN Hotels Rochester-Mayo Clinic Area, an IHG Hotel (507-322-6317)
3-star hotel; A "Wellness Hotel." Patient discount fluctuates based on availability. Located next door to Anderson Wheelchair Rentals. Connecting rooms available but not guaranteed. EVEN is located in the same building as Staybridge Suites.
- COE Discount Available
- Connecting Rooms Available
- Handicap Accessible
- Courtesy Clinic Shuttle
- Google Top 5 Reviews
Fairfield Inn & Suites Rochester Mayo Clinic Area/Saint Marys (507-258-7300)
2.5-star hotel; Patient discount fluctuates, depending on the date. They are almost always able to fulfill connecting room requests and won't make the reservation if they can't. Be sure to ask for your recliner when you make your reservation. The height of the bed can be lowered upon request.
- COE Discount Available
- Recliner Available
- Connecting Rooms Available
- Handicap Accessible
- Courtesy Clinic Shuttle
- TripAdvisor Top 5 Reviews
Hampton Inn & Suites-Rochester-North (507-289-6100)
3-star hotel; Patient discount is approximately 25% but varies by date and availability. Many rooms have recliners in them already, but be sure to request one upon reservation if you need it.
- COE Discount Available
- Recliner Available
- Handicap Accessible
- Courtesy Clinic Shuttle
Hilton Garden Inn Downtown Rochester (507-285-1234)
3-star hotel; Mayo Clinic patient rate varies based on how full the hotel is. Connecting rooms can be guaranteed at time of reservation. Suites have recliners in them, and a recliner can be moved to any room for a $25 fee.
- COE Discount Available
- Recliner Available
- Connecting Rooms Available
- Handicap Accessible
- Skyway/Subway Connection
- Courtesy Clinic Shuttle
Hilton Rochester Mayo Clinic Area (507-258-5757)
3-star hotel; Mayo Clinic patient rate varies based on date and how full the hotel is. Guaranteed connecting rooms can only be booked online. Make your request for a recliner at the time of reservation.
- COE Discount Available
- Recliner Available
- Connecting Rooms Available
- Handicap Accessible
- Skyway/Subway Connection
- Courtesy Clinic Shuttle
- TripAdvisor Top 5 Reviews
- Google Top 5 Reviews
Home2 Suites by Hilton Rochester Mayo Clinic Area (507-361-4200)
3-star hotel; Mayo clinic patient rate is 15-20% off, varying by day of the week. They can't guarantee connecting rooms but do their best to accommodate.
- COE Discount Available
- Connecting Rooms Available
- Kitchenette
- Handicap Accessible
- Courtesy Clinic Shuttle
- TripAdvisor Top 5 Reviews
- Google Top 5 Reviews
Hotel Indigo Rochester Downtown (507-252-8200)
3-star hotel; Patient rate fluctuates based on how full the hotel is, but is generally between $92-$149. Connecting rooms cannot be guaranteed.
- COE Discount Available
- Connecting Rooms Available
- Handicap Accessible
- Skyway/Subway Connection
Kahler Inn & Suites (507-285-9200)
3-star hotel; Mayo patient discount varies depending on day and room type. Make your request for a recliner at the time of reservation.
- COE Discount Available
- Recliner Available
- Kitchenette
- Handicap Accessible
- Skyway/Subway Connection
- Courtesy Clinic Shuttle
Rochester Marriott Mayo Clinic Area (507-280-6000)
3-star hotel; Patient rates vary by date and occupancy. Connecting rooms cannot be guaranteed.
- COE Discount Available
- Connecting Rooms Available
- Handicap Accessible
- Skyway/Subway Connection
- Courtesy Clinic Shuttle
Staybridge Suites Rochester-Mayo Clinic Area, an IHG Hotel (507-322-6318)
3-star hotel; Patient discount fluctuates based on availability. Anderson Wheelchair Rentals is located next door. Connecting rooms are available but not guaranteed. Staybridge Suites are located in the same building as EVEN Hotel.
- COE Discount Available
- Connecting Rooms Available
- Kitchenette
- Handicap Accessible
- Courtesy Clinic Shuttle
- Google Top 5 Reviews
Short-Term (AirBnB/VRBO)
Short-term rentals are available in the Rochester area, and the list below includes sole occupancy/single unit properties, some of which have one or more accessibility features. Review each individual listing for specifics.
Mayo in 2 Blocks NO STEPS/Elevator Private Code
Average review (1-5): 4.7
- Apartment/Condo
- Self check-in
- Onsite laundry
- Kitchen
- Onsite parking
WALK to Mayo-8074- Charming Main Floor 1BR apt
Average review (1-5): 4.63
- Apartment/Condo
- Self check-in
- Onsite laundry
- Kitchen
- Onsite parking
Half mile to Mayo & Downtown-Fast Wi-Fi-2 Bedroom
Average review (1-5): 4.76
- Apartment/Condo
- House
- Self check-in
- Kitchen
- Onsite parking
Luxury and Local Charm | 3 Blocks From Mayo
Average review (1-5): 5
- House
- Self check-in
- Onsite laundry
- Kitchen
- Onsite parking
- Long term stay discount
- Pets allowed
REMOTE WORKSPACE WALK→MAYO FAST WIFI Cozy
Average review (1-5): 4.7
- Apartment/Condo
- Onsite laundry
- Kitchen
- Onsite parking
Travel information is provided through a collaboration between The Hypertrophic Cardiomyopathy Association and Reasonable Accommodations LLC.
The HCMA and Reasonable Accommodations will make their best effort to keep the Patient Travel Planning Guide as current as possible. The HCMA cannot give any guarantees with regard to the prices, opening times, and availability of any specified facilities. Additionally, just because facilities are mentioned does not necessarily mean that these will always be available. Changes may also have been made to the specified prices, opening times, and availability.
