News
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Mavacamten Affects Diastolic Dysfunction
Background HCM patients commonly suffer from diastolic dysfunction(also called heart failure with preserved ejection fraction (HFpEF), or left-sided heart failure): their hearts do not…
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Expert Consensus on Syncope in HCM
An expert panel of HCM clinicians and researchers has published ( Brignole et al. 2022) a set of guidelines for diagnosing the causes of…
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ACC: ORIGINAL INVESTIGATIONS Myosin Inhibition in Patients with Obstructive Hypertrophic Cardiomyopathy Referred for Septal Reduction Therapy
BACKGROUND Septal reduction therapy (SRT), surgical myectomy, or alcohol ablation, is recommended for obstructive hypertrophic cardiomyopathy (oHCM) patients with intractable symptoms despite maximal medical…
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Training and Experience Count: Myectomy Is Safest at High-Volume Centers
Large study of US myectomies Myectomy is safest at high-volume centers. A study accepted in The Annals of Thoracic Surgery provides new evidence of…
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Cytokinetics Aficamten Research
REDWOOD-HCM OLE REDWOOD-HCM OLE: First Long-Term Data from Open Label Extension Cytokinetics’ also announced positive data relating to aficamten from REDWOOD-HCM OLE ( R…
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Updated Thinking on HCM Genetics
Quick summary Since around 1990, HCM has been regarded as a disease caused entirely by single mutation s in genes affecting a protein in…
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Mavacamten Instead of Septal Reduction?
Many people first discover they have HCM because blood flow out of their heart is obstructed. Some of these patients eventually need to have…
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Two New State-Of-The-Art Reviews on HCM
An expert panel of HCM doctors published two state-of-the-art reviews in the Feb. 1, 2022 issue of Journal of the American College of Cardiology.…
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ICER Publishes Final Evidence Report and Policy Recommendations on Mavacamten for Hypertrophic Cardiomyopathy
ICER has released its evidence report and recommendations. Here is a list of highlights: To read the entire report click here The post ICER…
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Weight Loss Improves HCM Patients’ Heart Health
Weight management is a challenge for many. Losing weight is a challenge for nearly everyone who tries it. It can be more difficult for…
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Consequences of Obesity for Health in HCM Patients
Weight management can make a big difference for HCM patients. That’s not just something cardiologists say to lecture you. A 2020 paper, Association of…
